6 Surprising Benefits of Turmeric In Skin Cancer [UPDATED]

Skin cancer is the malignancy in the different types of cells of the outer covering of the human body, the skin.
The types of cells in the skin in which cancer may develop are the basal cells, squamous cells or the melanocytes (melanin producing cells).

The basal cell cancer and squamous cell cancer are classified as non-melanoma skin cancer, while the cancer in melanocytes is called melanoma. Non-melanoma is more common and easy to treat while melanoma is rare but a dangerous form.

Melanoma form often spreads to other parts of the body, if not diagnosed early. It may also arise from pre-cancerous moles present on the body.

Skin cancer generally forms on face, head, neck, hands and arms. It is mostly caused by exposure to sun. The Ultra-Violet (UV) radiations from the sun damage the DNA of the skin cells which may gradually develop into cancer.

The common symptoms of skin cancer are presence of sore or ulcer that does not heal within a month, scaly and itchy brown patch on the skin, moles whose appearance change and appearance of white & waxy lump.

The risk factors for skin cancer besides exposure to sun include having a light skin and freckles, old age, severe sunburns, family history, presence of a number of large and thick moles, and using UV tanning beds.

People with certain skin diseases such as Xeroderma pigmentosum, Psoriasis are at a greater risk of developing skin cancer. Weak immunity and exposure to carcinogens like coal, tar, arsenic etc and radiations like radium also increase the risk of skin cancer.

Depending upon the severity and type of the skin cancer, the treatment strategy is adopted. Chemotherapy (topical or oral), radiotherapy, surgery or immune-therapy is common treatment options.

The treatments like chemotherapy and radiotherapy have many side-effects such as skin irritation, blistering, change in skin colour, acne, increased sensitivity to sun, hair loss etc. In case of oral chemotherapy, the side-effects like fatigue, nausea, increased risk of infection are common.

The natural remedies are considered to avoid these side-effects and to improve the effect of treatment for skin cancer.

Owing to its wide range of medicinal properties, turmeric is a good candidate for the natural remedy of skin cancer.

What is turmeric?

Turmeric, a popular spice used for its flavour and colour, is obtained from the plant Curcuma longa. It belongs to the family Zingiberaceae.

Besides its culinary application, it is used as a dyeing agent and in cosmetics. It is also a very important ingredient of traditional medicine.

Turmeric has long been used as an analgesic and anti-septic. It possesses a number of other medicinal properties that has attracted a lot of research in recent times.

The properties such as antioxidant, anti-inflammatory, immune-modulatory and anti-cancer are present in turmeric by the virtue of its bio-active compounds.

The most bio-active compound identified in turmeric is the curcuminoids, especially curcumin. The other compounds that make up turmeric are volatile oils, α-linolenic acid, omega fatty acids, Vitamins (B&C), minerals (Sodium, Potassium, Iron etc), proteins, dietary fibres, carbohydrates etc.

6 Surprising Benefits of Turmeric in Skin Cancer

The anti-cancer property of turmeric is of immense value against various types of cancer. The potential of turmeric against skin cancer is great, starting from the prevention to the treatment. Moreover, it has additional benefits against the side-effects of the conventional treatment methods.

1.Turmeric kills skin cancer cells

The abnormalities in the cells of skin due to various factors lead to the development of cancer. The treatment involves killing of these cells by various therapies which work by interfering in many molecular pathways.

Turmeric is a natural agent which works in the same way. Many studies have highlighted its ability to induce death in the cancer cells.

The role of oxidative stress and pro-inflammatory factors is central to the development of the skin cancer.

Curcumin, the chief component of turmeric is known to induce apoptosis or cell death in both the types of skin cancer, i.e. non-melanoma and melanoma.

In case of human basal cell carcinoma (a non-melanoma skin cancer), curcumin induces apoptosis by increasing levels of p53 protein (a pro-apoptotic protein).

In case of melanoma cells, curcumin induced cell death by increasing the expressions of various pro-apoptotic factors like Bax, p38 and p53. It also inhibited the activation of anti-apoptotic factors like Bcl-2 and Mcl-1.

Curcumin is also known to modulate microRNAs which are involved in cell cycle regulation and apoptosis.

What does it mean?
It means turmeric can be used in the treatment of skin cancer. It induces apoptosis in both the non-melanoma and melanoma cells by interfering in various molecular pathways.

2.Turmeric inhibits angiogenesis and tumour growth

The development of blood vessels or angiogenesis is involved in the growth of skin cancer, like the other cancers. The various angiogenic factors such as, VEGF (Vascular endothelial growth factor) are found to be elevated in the tumours. VEGF is considered to play a very important role in the development of skin cancer.

Inhibition of angiogenesis is seen as an effective way of treating skin cancer.

The turmeric compound, curcumin is a potent inhibitor of angiogenesis. It inhibits various molecules of the signal transduction pathways involved in the angiogenesis process.

Curcumin application on squamous cell carcinoma is found to result into reduced tumour progression by inhibition of MTOR pathway (involved in cancer proliferation by regulating cell cycle).

Its ability to prevent the invasion of cancer is also evident in melanoma. Curcumin suppressed proteins involved in Akt, MTOR and P70S6K signalling pathways that are involved in cancer progression.

What does it mean?
It means application of turmeric can inhibit angiogenesis and suppress tumour progression. The inhibition of various signalling pathways involved in angiogenesis and tumour progression by curcumin is responsible for the effectiveness of turmeric in this.

3.Turmeric boosts immune system to fight skin cancer

The role of immune system is integral to the development of skin cancer. A suppressed immune system is known to be related to the skin cancer. UV exposure leads to dysfunction of certain cells of immune system like T cells, eventually causing immune-suppression.

Immune system can control cancer by identifying them from normal cells and then destroying them.
Immune-therapy, i.e. boosting immune system is considered another viable treatment approach towards the treatment of skin cancer.

Curcumin, the major turmeric constituent is known for its immune-modulatory action on various aspects of the immune system.

It boosts the immunity by regulating activation of immune cells (T-cells, B cells) which enables the body to fight various immunity related diseases, including skin cancer.

What does it mean?
It means consumption of turmeric can boost the immunity of the body. The modulation of immune cells by curcumin enhances the capacity of the body to fight the skin cancer through better immune responses.

4.Turmeric protects from UV radiation and other carcinogens

The primary cause of skin cancer is ultra-violet (UV) radiation from the sun. UV rays damage the skin cells to cause cancer by causing mutations in their DNA as well as through immune-suppression.

Many environmental pollutants act as carcinogens for skin cancer. Skin is readily exposed to these carcinogens such as benzene, ozone, heavy metals (eg. arsenic, lead), which may lead to skin cancer.

A number of herbal compounds are known to protect the skin from UV ray, including turmeric. Its antioxidant activity prevents the damage caused by UV radiations by scavenging the free radicals. Its anti-inflammatory action also helps in this.

In a study, turmeric extract application on skin has shown the protective effect against the damages caused by UV exposure.

Turmeric is known to prevent chemical induced skin tumors as well.

In a study, dietary administration of turmeric significantly suppressed the skin tumours induced by a chemical DMBA (dimethylbenzanthracene).

The essential oil of turmeric prevents mutations caused by chemical mutagens like sodium azide, nitrophenylenediamene (NPD) etc.

Turmeric is also shown its protective action against the damages caused by arsenic in the body. Curcumin reduces the oxidative stress caused by arsenic and protects from DNA damage.

What does it mean?
It means use of turmeric can protect the body from the physical and chemical agents that can cause skin cancer. Turmeric prevents the damage caused by UV rays and other carcinogens to the skin cells by its antioxidant and anti-inflammatory action.

5.Turmeric protects from the side-effects of chemotherapy and radiotherapy

The major therapies employed for the treatment of skin cancer are chemotherapy and radiotherapy. These therapies are known to cause mild to severe side-effects.

5-Fluorouracil (5-FU) is a chemotherapeutic drug which is used both, orally or topically in the treatment of the skin cancer.

Oral 5-FU causes severe toxicities to heart, intestine and nervous system. Its topical application is also known to cause skin irritation and infections.

Many studies have proven the beneficial effect of turmeric against these toxicities. Curcumin is known to protect the intestines from the damage caused by 5-FU treatment.

The antioxidant and anti-inflammatory activities of curcumin play protective role against various adverse effects on the heart and nerves.

Imiquimod is an immune-modulator used in the treatment of skin cancer. It is known to induce psoriasis like condition. The application of curcumin gel significantly reduces the inflammation induced by imiquimod, due to its anti-inflammatory action.

Radiotherapy is also known to cause side-effects such as radiodermatitis. Application of turmeric based cream on the skin ameliorates the condition and also reduces itching and pain.

What does it mean?
It means consumption of turmeric and its topical application can protect against a number of mild to severe side-effects caused by chemotherapy and radiotherapy.

6.Topical turmeric is as good as dietary turmeric in skin cancer

The dietary use of turmeric is well-known for its anti-cancer activities in numerous types of cancers. In the skin cancer as well, dietary consumption of turmeric displays its protective effects.

Dietary antioxidants prevent the damage to skin cells by quenching the free radical generated by exposure to UV rays or other carcinogens.

Curcumin from turmeric works in the same manner and prevents tumour progression on the skin.

Nowadays, topical application of turmeric is also employed in the skin cancer treatment which has proven to be efficacious.

A study was conducted to compare the efficiencies of the dietary and topical curcumin in a skin cancer model. It was observed that the topical curcumin was equally effective as the dietary curcumin in suppressing the tumour growth on the skin.

What does it mean?
It means for the treatment of skin cancer, topical use of turmeric is as effective as the dietary turmeric. So, turmeric paste or turmeric based ointments, gels or creams can be used to treat the skin cancer.

Dosage of Turmeric for Skin cancer

The dietary use of turmeric is highly beneficial in preventing all types of cancer. For skin cancer, turmeric can be used in diet as well as for topical application.

The main bio-active component of turmeric, i.e. curcumin has a poor bioavailability. Therefore, it should be mixed with black pepper and/or healthy fats such as coconut oil to improve its absorption by the body. (Read How to improve turmeric’s bioavailability?)

High dosage of curcumin is needed for the cancer treatment. Therefore, use of turmeric supplements is recommended. A dose schedule can be followed by skin cancer patients from the article Turmeric/ Curcumin Dosage for Cancer: A Scientific Plan.

Golden Paste is another good option for the turmeric’s dietary use. It is a paste made from fresh turmeric or its dried powder combined with black pepper and healthy fats.

Turmeric intake should be started off with lower doses (1/4-1/2 teaspoon per day for a week) and can be elevated gradually over a few weeks to 2-3 teaspoons per day, if no side-effects are detected.

Turmeric supplements and Golden Paste may cause acid reflux if taken in on an empty stomach. (Read Does turmeric cause acid reflux?)

Turmeric supplement consumption is not recommended at the same time as other medicines because it can interact with certain medications. A gap of at least 3-4 hours is necessary to be maintained between the two. (Read Black pepper in GP: Does it cause drug interaction?)

If not taking Golden Paste or turmeric supplements, turmeric intake is highly valuable in the regular diet to prevent and treat skin cancer.

Turmeric powder or fresh root can be used in soups, rice dishes, smoothies, curries or other dishes. Half-an-inch of fresh turmeric root or its juice is also a good way of taking in turmeric.

Topical use of turmeric for skin cancer

Turmeric can be applied topically by the skin cancer patients on the affected areas of the skin.

A patch test should be conducted prior to the use. If no side-effects are observed turmeric can be applied regularly.

For the topical application, turmeric powder should be mixed with oil, preferably coconut or olive oil. After applying this mixture on the affected area, it should be left for at least 30 minutes and the areas can be covered with gauze, if needed.

This should be repeated 2-3 times a day for best results.

Some good brands of organic turmeric can be found at our recommendation on best organic turmeric brands.

Precautions

Dietary turmeric is very safe but a few precautions need to be considered when it comes to turmeric supplements (Read Side effects of curcumin Side effects of Turmeric):

  • Avoid in pregnancy and lactation
  • Avoid if suffering from gall bladder obstruction
  • Avoid if suffering from a bleeding disorder
  • Discontinue prior to surgery

If suffering from gout or at risk of developing kidney stones, limit intake of turmeric as a spice. (Is turmeric safe in gout? Does turmeric cause kidney stone?)

Avoid taking turmeric on an empty stomach to avoid acid reflux symptoms. (Does turmeric cause acid reflux?)

If suffering from a bleeding disorder, small doses of turmeric in diet are safe but it is best to consult a doctor before taking turmeric or turmeric supplements in this case. (Is turmeric a blood thinner?)

A general precaution is outlined that turmeric may have drug interactions with stomach acid reducing medication, antidepressants, blood sugar reducing drugs etc. Curcumin found in turmeric is known to interfere in drug metabolism. Hence it is advised not to take curcumin supplements concomitantly with any other medicine.

Consult a health practitioner before taking turmeric supplements for skin cancer.

Conclusion

Turmeric is an extremely beneficial natural product against skin cancer.

Its diverse biological properties not only can treat the different types of skin cancer, but also can prevent their occurrence.

The antioxidant and anti-inflammatory action of turmeric checks the damages caused to the skin cells by a number of carcinogens, most notably the UV radiation that have potential of causing cancer.

Moreover, turmeric protects the body from various side-effects caused by the conventional treatments against the skin cancer.

Furthermore, the topical and dietary turmeric are equally efficacious and thus, provide diversity for turmeric use against the skin cancer.

 

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22 Comments

  1. I must try this technique. I always prefer older people to consume the turmeric powder which is only and best solution to fight with Diabetes, Arthritis, Lower down cholesterol levels and sort out liver ailments.It works as an antioxidant, anti-inflammatory, anti-bacterial and anti-viral agent. It is curcumin that gives turmeric its potent healing properties.

  2. Hi, I have just been diagnosed with Basil skin cancer on my nose and it’s really small right now. I have been reading the others with skin cancer and using the Turmeric. I am looking into this now. Any suggestions would be helpful. I was diagnosed few years back with Fibroids possibly by a ER doctor and not treated properly and also been tortured with what like believe is a very large tape worm of some sort and been on herbs and even poison to kill it and Heavy detox for over a year now which has cost me thousands of dollars.
    I feel the tape worm or whatever it might be has caused the skin Cancer to pop up.
    I could feel something on outside of my body for long time as well inside.
    Not one doctor l saw for several colon checks and scope nothing showed up but could sure feel it.
    Hospitals either would help. I am 100% they know and just don’t care enough to have taken it out and now have this new skin cancer showing up.
    Please help give me advice on this new development which truly l didn’t need. I have had about 6 car accidents and lost a child and also know while l was a child soldier trained and off l went to Vietnam back in early sixties that l was also exposed to Agent Orange and does cause Skin Cancer and other forms l am sure.
    Been fighting the government over 20 years on this soldier thing in courts and I Want Answer’s to what the hell l was doing in Vietnam as a child trained by Canadian and American Government’s.
    This part of what l went through is the very reason l am having trouble with my Gut and some forms of parasite and skin issues!
    Please if you have heard of others with similar issue’s please let me know.
    Thank you, Susan

    1. Hi. Turmeric is an anti-microbial as well as anti-cancer agent. For cancer we recommend taking curcumin supplements and you can find details about dosage here:
      https://www.turmericforhealth.com/general-info/turmeric-curcumin-dosage-for-cancer-a-scientific-plan
      Consult a health practitioner before taking turmeric supplements.
      Topical application of turmeric may benefit in cancer
      https://www.turmericforhealth.com/turmeric-benefits/6-benefits-of-topical-turmeric-in-cancer
      The supplements may benefit in parasitic infection as well. You can also include turmeric in diet as Golden Paste.
      https://www.turmericforhealth.com/turmeric-recipes/how-to-make-golden-paste-from-raw-fresh-turmeric
      https://www.turmericforhealth.com/turmeric-recipes/how-to-make-turmeric-paste-or-golden-paste

    2. Susan;

      Did you have any success? I have a similar problem on my nose. Would be interested in your experience….

  3. I’ve had great success with Turmeric in treating multiple Ovarian Cysts, a Carcinogenic Fibroid and Endometriosis. In the space of 7 months, straight after being diagnosed with the above (after scan in Dec 2015) I started taking a high strength Turmeric capsule almost everyday. Since the most recent scan in July, my Radiology scan results report: “No current evidence or appearance of any Cysts, cancerous or otherwise, no evidence of Endometriosis, Fibroid now appears to be significantly reduced to less than 1/2 the size of its first appearance”. All my blood tests had gone from abnormal to in the healthiest range of normal, and my Cancer Marker had gone way down to a now “not at risk” level. My Doctor was amazed at the results, as we had both thought (before reading the new results) that I’d be on the operating table again inside of a month. But this is not to be. Instead, I’m to have another Scan in 6 months to see if there is any further improvement. I am no longer considered at risk of any cancer.

  4. Any chance I could get the research study information. It means a lot to me as I’m considering refusing medical immunotherapy for metastatic melanoma and using turmeric and pepper. Would love to fully red research papers you quoted
    Thank you!

    1. Hi Joan, My husband has metastatic melanoma and has had great success so far with immunotherapy, 11 months since diagnosis. We had a dermatologist recommend turmeric supplements, that MD Anderson is giving them to their patients, but we asked our team of oncologists and they said not to take it, that immunotherapy is trying to boost your immune system and turmeric would be trying to suppress it. So for now we are happy to follow medical advice but if there is new research out there that supports taking turmeric alongside immunotherapy I would be willing to listen. I hope this note finds you well and wish the best for you.

      1. I am a 2 time survivor of melanoma. Stage 3 and stage 1. I took interferon (immunotherapy) in 2001-2002 and beat the statistics for survival. At the time only 15% made it past the 5 year mark. Immunotherapy DOES work!! My 2nd melanoma in 2005 was detected very early so I only needed major surgery to defeat it. I am 11 years cancer free and 15 years out from the stage 3 diagnosis. My doctors at Moffitt Cancer Center in Tampa FL were amazing. As rough as interferon was (and the lifelong side effects that I now have), I would do it again.

    2. Yes this is an interesting point. There has been research which shows that curcumin is beneficial in terminating melanoma cells but it may interfere with immune responses.
      http://www.ncbi.nlm.nih.gov/pubmed/19723881
      However some studies show that curcumin can strengthen immune responses in fighting cancer.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603973/
      Dietary turmeric is unlikely to cause any problem and instead would help fight cancer. You can take Golden Paste at a dose of 1/4 to 1/2 tsp a day and then increase the dose gradually. Avoid taking it near consumption of medicines and best taken with meals.
      https://www.turmericforhealth.com/turmeric-recipes/how-to-make-turmeric-paste-or-golden-paste

  5. Hi Erin,
    3cc was a watery solution, not a paste and my curcumin capsule was granular and didn’t dissolve.
    Can you mention the brands you used, it seems as if 1/2 cc of ACV would be plenty. Thank you for posting!

  6. I have been mixing Golden Paste with Bentonite clay and treating some skin cancers as I want to try this before I try the recommended chemo cream the Dr prescribed. I have researched the cream and it sounds like a total nightmare, so if the Turmeric can do the trick I am willing to give it a jolly good shot first. Do you think adding the Bentonite clay is a good idea? Also have been leaving the mixture on and covering it with a dressing, applying once a day. Should I be doing it more often? Thank you for such a great site. Between you and TUG on FB I have loads of good Turmeric info 🙂

    1. Hi Peral, thanks a lot for appreciating my modest effort with the portal. TUG is just amazing, the admins are awesome and community is so helpful.

      Regarding your query, I am not sure how much help Bentonite clay can do. It is for sure good for skin disorders such as eczema, etc. Are you already trying it or will be doing it now? Please keep me posted.

      1. I am interested in tumeric as a cream/paste to prevent/possibly slow down early skin cancerous cells. Is there any update on this story? Does anyone know where I might be able to find a recipe to make the cream or is there a cream on the natural medicine market?

        1. Hi Jane. I have successfully treated basal and squamous cell carcinomas (skin cancers) on myself, as well as removed two small genital warts on a friend, using this recipe: 3ml of Apple cider vinegar into which is added 1 capsule of green tea extract and 1 capsule of turmeric extract. The capsules are purchased in bottles and there are many brands out there; choose a strong extract. Make new batches as you need them. I make the watery paste in a narrow amber glass bottle that’s about 2 inches tall. Both turmeric and green tea extract are potent surface cancer removers and even better when combined.

          Once you have the watery paste ready, wash and scrub the problem skin patch. Shake the mixture well before use, and apply the wet paste thickly to the gauze part of a bandage and put that over your cancer or wart patch overnight for at least 12 hours. Take it off in the morning. Repeat this process using the bandage at night every second day for 14 days and the problem should be gone! You’ll notice that after just a day or two the problem skin patch (if it’s actually cancerous or HPV warts) will turn a very dark crusty brown while the rest of the skin doesn’t react like that to the paste at all. Whenever the dark crust gets loose after a few days I gently peel it off to enable the paste to get at deeper layers so that no cancer cells are left behind. I have only ever tried this on small patches of skin smaller than the size of a dime.

          It may sting a little for a few minutes when first applied, generally just the first two or three times. After that the patch will be mostly gone. The majority of the problem cells are killed in the first 3 or 4 days of treatment and after that the reaction is just getting the last few problem cells left.

          Turmeric spice paste also worked applied to filiform warts just inside a nostril (without using the apple cider vinegar, just the turmeric paste). Best of all, there’s been absolutely no sign of any of these skin conditions returning, and at this point it’s been a few years with no recurrence! I’m currently treating a small carcinoma plaque on my right calf that I’ve had for over two decades and it’s about 80% gone now after just six days of treatment!

          FYI: If the patch is not actually a wart or cancer your skin won’t react to the paste and won’t develop that dark brown crust. It’s amazing how specific and effective this treatment is!

          1. Hi Erin, Please tell me – what brand turmeric and green tea extract capsules do you use?
            Can this be applied to an open cancer growth (one that is on the surface, oozing, painful ..)?
            Some topical cancer treatments make things swell before they go down, is this the case with the Apple Cider Vinegar / Tumeric / Green Tea Extract? I wouldn’t think so – I would think it is the opposite, anti inflammatory, makes things go down right away. Just wanting to know what to expect though. Thank you so very much.

          2. Hi Erin, you sound so smart. I would love to talk to you, phone, e-mail???
            I am fighting squamish cell cancers in my legs below my knees.
            I have been making a paste of Turmeric, oil and pepper. So far I haven’t seen any change in them.
            I am a very healthy 71 yr. old and I feel like this cancer is going to kill me.
            I have biopsies— mohs surgery — and then more come. I decided I am done with these doctors!! I want to do it myself, like you did.
            I wonder if it is okay to give you my e-mail address and maybe I will hear from you. I guess it won’t if you no longer get on this website.
            It is [email protected] just in case you get this.
            Thanks so much.
            Bev

          3. Hi Bev. Are you using good quality organic turmeric powder? How frequently are you applying the paste and for how long. Do not include black pepper for topical application. One addition that you could make to the topical paste is to find standardized 95% curcumin powder and add it to the paste. You could also break open capsules for the same.
            We have a guide on dosage for oral curcumin and cancer that might help you.
            https://www.turmericforhealth.com/general-info/turmeric-curcumin-dosage-for-cancer-a-scientific-plan
            https://www.turmericforhealth.com/turmeric-benefits/6-benefits-of-topical-turmeric-in-cancer

          4. Erin, I tried your recipe to cure a squamous skin cancer on my leg and was getting good results, but after two weeks of treatment it was still not healed, so I gave up. Did I give up too soon? Also, I would like to know if you used the type of curcumin which contains pepperine for better absorption. This would be helpful to know as I am considering using your curcumin treatment again. I am trying to avoid mohs surgery.