It occurs when oxygen-rich blood does not reach the heart muscles.
Heart attacks are mostly consequences of Coronary Heart Disease where fatty deposits or plaque gets accumulated in the inner walls of arteries which supply oxygen-rich blood to the heart.
Severe coronary heart disease is treated by a type of surgery called Coronary Artery Bypass Grafting (CABG).
However, some complications may occur just after (in-patient) CABG which include stroke, heart attack etc. and may even lead to death.
Studies suggest that Curcumin, a natural plant-based polyphenolic compound obtained from Turmeric, suppresses inflammation and cardiomyocytic apoptosis caused after Cardiac ischemia/ reperfusion.
Following this, a research was conducted to test the efficacy of curcumin in forestalling Myocardial Infarction post Coronary Artery Bypass Grafting (CABG). We discuss that study here.
The study noted that”Adequate myocardial protection during CABG is crucial in preventing myocardial injury after surgery”.
The study was a random clinical trial comprising of 121 patients going through Coronary Artery Bypass Grafting.
Some of them were given placebo treatment while the rest received curcumin treatment, the dosage being 4g/day. The treatment started 3 days before surgery and ended after 5 days of the same.
The scientists noted the percentage of occurrence of Myocardial infarction in both the groups along with few secondary parameters likes levels of C-reactive protein, Plasma Malondialdehyde as well as levels of N-terminal pro–B-type natriuretic peptide.
It was observed that chances of Myocardial Infarction decreased more in the curcumin-treated group (13.1%) as compared to the placebo group (30.0%).
Comparison of secondary markers also produced results in favor of curcumin treatment indicating lesser inflammation , lipid peroxides and ventricular dysfunction in the curcumin group than the placebo group.
The study indicated that “curcuminoids decreased the incidence of in-hospital heart attacks after CABG significantly”. This is a good news.
While the results were positive, the study also mentions that more work is the direction is required using larger / extensive studies in this direction.