Research Study – Turmeric against Type2 Diabetes Mellitus and Atherosclerosis

Turmeric (curcuma longa) is a traditional Indian medicine.

Modern day research studies have found the potential of curcumin (which constitutes 3-4% of dry turmeric powder by weight) in preventing and curing a large number of diseases, thus, making it one of the most thoroughly researched natural compounds.

Type2 diabetes mellitus (T2DM) is a chronic condition that affects the glucose metabolism in the patient’s body.

The body either resists the effects of insulin or does not produce enough insulin leading to accumulation of glucose in the blood.

Since the disease is incurable, it is important to limit the number of cases with fully developed T2DM.
Role of curcumin against T2DM

A 2013 study published in the Journal of Nutritional Biochemistry along with a 2012 study published in American Diabetes Association’s Journal: Diabetes Care, explore how curcumin intervention can help in reducing the atherogenic risks in type 2 diabetes patients and preventing T2DM in pre-diabetic population respectively.

The results of both the studies were similar.

The 2013 research lasted for 6 months and was done on 226 patients suffering from T2DM . Various metabolic parameters like the stiffness of arteries were compared in the two groups i.e. the placebo-controlled and curcumin groups.

The anti-inflammatory effect of curcumin brought down the stiffness in arteries and leptin levels, and elevated adiponectin protein’s levels. Hence, abdominal obesity and resistance to insulin also decreased.

The 2012 research was a 9-month trial conducted on 240 subjects diagnosed with pre-diabetes.

All subjects were randomly given either 3 capsules of curcumin (250 g curcuminoid extract per capsule) or placebo (250 g starch per capsule) twice a day. Changes in beta-cell functions, insulin resistance, adiponectin levels, and other parameters were observed at baseline and after 3, 6 and 9 months.

After 9 months, no patient in curcumin group was suffering from T2DM in contrast to placebo group where 16.4% patients developed T2DM .

With lower insulin resistance and higher levels of adiponectin, the overall beta cell functioning enhanced in curcumin group than the placebo-controlled group.

Conclusion

Taking the results of the two research studies into consideration, it can be concluded that oral intake of curcumin in pre-diabetes can remarkably prevent Type 2 Diabetes Mellitus development by the maintenance of healthy beta cell functions.

Also, curcumin consumption in Type2 Diabetes Mellitus patients can lower down the risk of occurrence of cardiovascular complications like Atherosclerosis, that too with minimal/no side effects.

Read our detail article on Turmeric Benefits in Diabetes here

About the Author

TurmericForHealthTeam

Turmeric for Health's writer team consists of passionate writers from the fields of biotechnology, pharmacy, nutrition, Ayurveda & microbiology.Our writers are highly qualified with many having Ph.D., M.Tech & MSc degrees while others having B.Tech, BSc, B.Pharm. Our differentiation lies in researching and presenting ONLY FACTUAL SCIENTIFIC information. We spend 10s of hours to write a single article. Info of our articles is sourced from reliable scientific sources which are also provided as a link alongside for readers to refer if they want. You can read more about our team in the " About us" section.

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